James Davis

Coluracetam Reviews - What Is It?

WARNING: DO NOT BUY Coluracetam Until You Read This Review!
Is it a Scam? Does It Really Work? Check Ingredients, Side Effects and More!

Coluracetam is a racetam drug that possesses memory boosting properties and has a positive effect on anxiety and depression. However, there is lack of scientific proof to back up these benefits. More studies are required to identify the mechanisms behind these properties. Coluracetam was synthesized in Japan by the Mitsubishi Tanabe Pharma Corporation in 2005with the intention to treat Alzheimer's disease. However, it failed to reach certain endpoints and was licensed by BrainCells, Inc for additional research. The drug received the license from Mitsubishi Tanabe Pharma Corporation, BrainCells Inc. The testing of coluracetam effects started. But there were not enough people to take part in clinical trials, so most of these tests were made on rats. These tests showed that coluracetam was improved learning, memory, and anxiety. Nowadays, the product is not popular in the country, however, it has an official website. the latter doesn't seem to be informative enough, though.

Ingredients of Coluracetam - Does It Really Work? Is It a Scam?

According to the official website, this supplement is used to improve memory and cognitive function in rats. It is not completely correct, however, to say that the same results can be expected in human beings. One study on rats also found that a dosage of 240 mg was useful in the treatment of major depression. Coluracetam is associated with some benefits for eyesight. It is claimed to enhance recognition, color vision, and vividness. However, there is no conclusive evidence to back up the mechanisms behind this claim.


As far as you can see, the only ingredient in the product is coluracetam, a compound that works in the brain. Its full structural name is 2-(2-oxopyrrolidin-1-yl)-N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro2,3-b quinolin-4-yl)acetoamide and its codenames are KC-231 or BCI-540. This racetam compound is a nootropic that was created for cognitive enhancement. It is a completely synthetic drug, so there are no natural ingredients in the supplement. The product was made to support cholinergic function, including for the treatment of Alzheimer's.

Like other racetam compounds, coluracetam works by increasing choline uptake, in damaged neurons as well. It influences the HACU process which deals with the absorption of choline into the neurons. The supplement improves choline preservation in this process. Its big amount is converted into acetylcholine. As a result, you are expected to notice an increase in your attention, memory, and alertness. It should be emphasized that these benefits were seen only in those individuals who has impaired neurons. Individuals with normally functioning neurons did not experience any benefit.

Coluracetam is also claimed to improve the process that triggers cognitive function and is called AMPA potentiation. The compound does interact with choline transporters but there is no evidence to explain this interaction. One of my biggest concerns is that the drug was researched only with rats, thus there are no recommended dosages of the product for humans. Some users report dosing of about 3-35 mg up to 3x per day. However, it is recommended to start from a lower dosing in order to check your reaction to the supplement.

The official website of the supplement does not contain any information on possible toxicity of coluracetam. Low doses are not expected to lead to potential adverse reactions. However, some users do experience certain side effects. We will discuss this topic in the next part of this review. In any case, if you have never used a nootropic before, you are at a higher risk of getting a headache. This is a common effect in first-time users. You may combine coluracetam with a bioavailable choline source in order to decrease the chance of side effects.

Customer Reviews - Does It Have Any Side Effects?

The manufacturer of Coluracetam mentioned absolutely nothing about possible side effects of the product. The racetam class of drugs is considered to be generally safe in terms of side effects and toxicity. However, there is lack of studies for making such a bold claim, to my mind. Animal studies showed no signs of toxicity or adverse reactions, but there have been no studies involving human beings. So, you never known what to expect from this product.

Some users report experiencing disturbed sleep, headaches, and dizziness when using Coluracetam. This supplement may also cause shakiness, nervousness, or weight increase. To decrease these effects, you are recommended to drink plenty of water, to avoid taking Coluracetam before bed-time, and not to exceed the recommended dosages (up to 80 mg three times per day). It is still unknown whether this drug could be addictive or have tolerance build up. Let us have a look at some users' reviews.

"I bought Coluracetam and I did not benefit from it. This proves that fact that it does not work for everyone. It just gave me a big brain fog. I think this supplement contains something that is very bad for my health."

"I have read so many positive reviews on the staff online but why didn't coluracetam work on me. When I was ordering it, the girl said that it has high quality and would work just okay for me but I was very disappointed. I am afraid of increasing dosages."

"I have been taking Coluracetam for about two weeks but I haven't seen any improvement in my brain function. So yesterday I doubled the dosage. I regretted doing so because I experienced severe headache and dizziness."

Where To Buy Coluracetam?

Coluracetam is only available at some online retail stores. You can buy Coluracetam in powder form on Amazon. PeakNootropics, GNC and Walmart offers this product.

My Final Summary

Coluracetam is a very complex drug in the racetam family. It is a badly known nootropic associated with little research. The few studies on rats are promising, but more research on humans is necessary. This drug has a few good user reviews, as well as negative ones. Some people report suffering from headaches and some other side effects. I cannot recommend Coluracetam to usage. There are other more popular nootropics with enough scientific evidence for you to choose from.