James Davis

Xeljanz Reviews - What Is It?

WARNING: DO NOT BUY Xeljanz Until You Read This Review!
Is it a Scam? Does It Really Work? Check Ingredients, Side Effects and More!

Xeljanz is a new product that is used for the treatment of adults who suffer from moderate to severely active rheumatoid arthritis. It is said to be more effective than methotrexate. However, it is unknown whether this medication is effective and safe in people with hepatitis B or C, as well as in children. It should not be used by patients with severe liver problems. Xeljanz is available in the form of small pills which are promised to assist to stop the damage of joints. In fact, it is a Jak inhibitor which helps to decrease pain and symptoms of rheumatoid arthritis. The product can be taken alone. There is an official website which is not very informative though. It contains a lot of safety information but not a word about active ingredients in the supplement.

Ingredients of Xeljanz - Does It Really Work? Is It a Scam?

The manufacturer of the product does not disclose the main ingredients in Xeljanz which makes it difficult to predict the action of the medication on a separate individual. For this reason, you are highly recommended to consult your doctor before starting to use this product. The components in Xeljanz may be unnatural, allergic or simply harmful. They may be added in the wrong combination and interact with each other. There is no proof of the studies conducted on the main ingredients in the product.


According to the official website, Xeljanz is formulated with the citrate salt of tofacitinib. The latter is a JAK inhibitor. It is a white to off-white powder. It is water-soluble which means that it can be digested in the human organism. Tofacitinib citrate has a molecular weight of 504.5 Daltons and a molecular formula of C16H20N6O-C6H8O7.

Xeljanz is supplied as oral pills, white in color and round in shape. One film-coated tablet contains 5 mg of tofacitinib which is equivalent to 8 mg tofacitinib citrate. Each tablet also contains the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, HPMC 2910/Hypromellose 6cP, magnesium stearate, titanium dioxide, triacetin, and macrogol/PEG3350.

Janus kinase (JAK) inhibitor works to disrupt in signaling pathways. These activities occur deep inside the cells. These signaling pathways are known to play an important role in the inflammation associated with rheumatoid arthritis. It is believed that if those pathways are disrupted, the process of inflammation can be decreased. There is information about clinical trials with and without the use of a disease-modifying antirheumatic drug (DMARD), such as methotrexate, however, the results are not documentally confirmed. The manufacturer of Xeljanz claims that more than a half of patients felt an improvement in their RA symptoms. They experienced a reduction in swollen and tender joint counts. Three of the following indicators were improved: blood test that measures inflammation, physician assessment, patient assessment, pain scale, and functional questionnaire. However, during the same period of the study (three months) 26% of placebo patients experienced the same positive results. So, it is not known for sure what helped more - Xeljanz or time.

Customer Reviews - Does It Have Any Side Effects?

Xeljanz is associated with a high risk of side effects due to its active ingredient tofacitinib. Look for immediate medical help if you experience any of the following signs of an allergic reaction: difficult breathing; hives; swelling of your face, tongue, lips, or throat. The treatment with tofacitinib can cause serious and in some cases fatal infections. Stop using the drug and call your doctor immediately if you have the following signs of infection: chills, fever, tired feeling, night sweats; loss of appetite, stomach pain, diarrhea, a change in your bowel habits, or weight loss; sore throat, body aches, flu; pain or burning during urination.

Xeljanz can lower the body's ability to fight infections. So, you are never protected from such infections as tuberculosis (TB), and infections caused by fungi, bacteria, or viruses. There are reports of fatal cases caused by these infections. Ask your healthcare provider to test you whether you can use the product without adverse reactions. Ask also for monitoring you for symptoms of TB infection during the treatment. Do not use Xeljanz if you have any kind of infection. You may be at a high risk of getting shingles.

Before starting to use the product, tell your doctor if you have HIV, diabetes, or a weak immune system; have or have had hepatitis B or C; TB, or have been in contact with someone with TB; have traveled to certain parts of the country where there is a high risk of getting fungal infections (coccidioidomycosis, histoplasmosis, or blastomycosis). These issues may become more severe if you use Xeljanz. Cancer and immune system problems are a big restriction to use this drug because it may increase your risk of lymphoma and other cancers.

There is a report that some people who have taken Xeljanz with certain medicines to prevent the rejection of a kidney transplant have had their white blood cells growing. There is a risk of getting tears in the stomach and intestine when taking Xeljanz in combination with corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), or methotrexate. Let's see what real users say about the product.

"I have serious fibrous complications after the use of another medication, so my doctor prescribed me Xeljanz. I have been using it for about a month and I don"t feel good. I suffer from pain in my hands and feet. I am going to see my doctor in a few weeks and I hope he can prescribe me something more effective."

"I took xeljanz for about two months. As a result, I lost my voice, got severe sore throat, headache and sinus issues. I also feel tired all the time and have trouble sleeping. Even after ceasing to use the drug I can't get rid of the burning in my throat. I don't think it is a safe drug."

"I took Xeljanz only one day and the next day I had upper respiratory irritation and a full blown sinus, fever, and headache. I was suffering for five days. I am going to look for a safer and more effective product available currently on the market."

Where To Buy Xeljanz?

Xeljanz is available on many Canadian retail stores including Online pharmacies Canada, Canada Drugs, Big Mountain Drugs. The cost of one pill is about $30-37. It is a VERY expensive drug. You will not find it on Amazon, GNC or Walmart.

My Final Summary

As a specialist I cannot recommend Xeljanz to usage by people with rheumatoid arthritis. This medication has a great number of side effects, it often leads to complications of the current user's health conditions. Besides, it is not always effective despite its high cost. I would advise looking for another safer medication and to talk to your doctor first. I am sure there are more effective ways of treating rheumatoid arthritis nowadays.